N,α-Diethylphenethylamine or N,alpha-Diethylphenylethylamine (N,α-DEPEA) is a close chemical analog of methamphetamine. It was originally patented, by Knoll Pharma as one of several analogs for pharmaceutical applications. In animals models these analogs showed properties of cognitive enhancement and increased pain tolerance. Nevertheless, this class of compounds was never developed into a medicine. N,α-DEPEA has not been studied in humans, but experts such as Pieter Cohen, an assistant professor of medicine at Harvard Medical School, expect it to be less potent than methamphetamine but greater than ephedrine.